Key result
Preoperative BNP concentrations correlated with aortic cross-clamp time (r2=0.32, P=0.006) and postoperative troponin I (r2=0.22, P=0.0009), and predicted long-term mortality after CABG.
Why the study?
Do A-type and B-type natriuretic peptide levels predict long-term mortality in patients undergoing cardiac surgical procedures?
Population
105 patients undergoing cardiac surgical procedures, including coronary artery bypass grafting with or…
Design
Cohort
Follow-up
up to 730 days (2 years)
Authors
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Preoperative BNP may refine long-term mortality risk stratification after CABG; leaves open whether measurement improves outcomes or should guide care.
Observational (n=105)
Do A-type and B-type natriuretic peptide levels predict long-term mortality in patients undergoing cardiac surgical procedures?
Preoperative BNP, but not ANP or postoperative BNP, is a significant predictor of long-term mortality in patients undergoing coronary artery bypass grafting.
Berendes et al. (2004) conducted an observational in Patients undergoing cardiac surgical procedures (n=105). Preoperative A-type and B-type natriuretic peptide (ANP and BNP) concentrations was evaluated on Postoperative mortality up to 730 days and correlation with surgical factors (aortic cross-clamp time and troponin I). Preoperative BNP concentrations correlated with aortic cross-clamp time (r2=0.32, P=0.006) and postoperative troponin I (r2=0.22, P=0.0009), and predicted long-term mortality after CABG.
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