Key result
Preoperative grade III-IV aortic insufficiency did not significantly impact early mortality (3.2% vs 5.7%, P=0.961) or midterm reoperation rates compared to grade II or less in valve-sparing surgery.
Why the study?
Does preoperative degree of aortic insufficiency influence early and midterm outcomes of aortic valve-sparing surgery in patients with aortic root aneurysm?
Cohort (n=84)
Does preoperative degree of aortic insufficiency influence early and midterm outcomes of aortic valve-sparing surgery in patients with aortic root aneurysm?
Preoperative degree of aortic regurgitation does not significantly impair early or midterm outcomes of aortic valve-sparing surgery in patients with aortic root aneurysm.
Answers are grounded in this paper and cite their sources.
Severe aortic insufficiency was not associated with worse early/midterm outcomes after valve-sparing surgery; hypothesis-generating and should not yet change practice.
OBJECTIVE: Aortic valve-sparing operations have shown excellent results in patients with aortic root and or ascending aorta aneurysm. Aortic valve regurgitation is frequently detected in these patients as a result of significant dilation of the aortic root.The aim of this study was to assess the impact of preoperative aortic incompetence degree on the early and midterm outcomes of sparing surgery. METHODS: From September 2001 to July 2006, 84 patients with aortic root aneurysm underwent aortic valve-sparing surgery according to the reimplantation technique. Depending on preoperative grade of aortic insufficiency (AI), two groups were identified: 31 patients (study group, SG) with AI grade III-IV and 53 (control group, CG) with AI grade II or less. The Gelweave Valsalva prosthesis was used in 76 patients (90.5%). Intraoperative, perioperative variables and outcomes at follow-up were retrospectively compared between the groups. RESULTS: Patient demographics and types of operations were comparable between groups. Early mortality rates were almost identical in both groups (3.2% SG vs. 5.7% CG; P = 0.961); at follow-up (FU), no patient died in both groups. Grade III-IV AI was similar in both groups early postoperatively (6.4% SG vs. 3.8% CG; P = 0.981) and during follow-up (13.3% vs. 8%; P = 0.755). Reoperaton rate for AI was 3.3% in SG vs. 6% in CG (P = 0.980). CONCLUSIONS: Preoperative degree of aortic regurgitation does not impair the outcomes of the valve-sparing operation which seem to depend on more factors. Early results were affected by the learning curve but midterm outcomes showed a progressive improvement. Patients with satisfactory reconstruction show stable results over time.
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Davide Pacini (2009) conducted a cohort in Aortic root aneurysm (n=84). Preoperative aortic insufficiency grade III-IV vs. Preoperative aortic insufficiency grade II or less was evaluated on Early mortality (p=0.961). Preoperative grade III-IV aortic insufficiency did not significantly impact early mortality (3.2% vs 5.7%, P=0.961) or midterm reoperation rates compared to grade II or less in valve-sparing surgery.
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