Key result
South Asian ethnicity was associated with a higher incidence of coronary disease (HR 1.35; 95% CI 1.30-1.40) but lower mortality once manifest (HR 0.78; 95% CI 0.74-0.82) compared to white subjects.
Why the study?
Does South Asian ethnicity affect the incidence and prognosis of coronary disease compared to white ethnicity?
Population
South Asians and white subjects in studies of incidence and prognosis of coronary disease, including an…
Comparison
South Asian ethnicity vs White ethnicity
Design
Meta-analysis
Follow-up
1 year (for ACS cohort)
Authors
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Supports prioritizing primary prevention in South Asians; extends meta-analytic evidence on ethnic disparities in coronary incidence versus survival.
Meta-Analysis
Yes
Does South Asian ethnicity affect the incidence and prognosis of coronary disease compared to white ethnicity?
Hazard Ratio: 1.35 (95% CI 1.3–1.4)
South Asian ethnicity is associated with a higher incidence of coronary disease but lower mortality after disease onset compared to white populations, suggesting a need for primary prevention focus.
Zaman et al. (2013) conducted a meta-analysis in Coronary disease. South Asian ethnicity vs. White subjects was evaluated on Incidence of non-fatal myocardial infarction or fatal coronary heart disease (HR 1.35, 95% CI 1.30 to 1.40). South Asian ethnicity was associated with a higher incidence of coronary disease (HR 1.35; 95% CI 1.30-1.40) but lower mortality once manifest (HR 0.78; 95% CI 0.74-0.82) compared to white subjects.
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