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September 6, 2026Health Psychology

Mindfulness-based stress reduction interventions and cortisol regulation: A systematic review and meta-analysis.

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Authors

BJBlair T. JohnsonTSTaryn J. SimonCLChen Li

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Overview

Systematic review and meta-analysis reveals reduced cortisol following mindfulness-based stress reduction, indicating meaningful physiological benefits for individuals facing chronic stress.

Key Points

  • To evaluate the specific impact of mindfulness-based stress reduction programs on physiological cortisol regulation through a pooled meta-analytic review.
  • Conducted a systematic review and meta-analysis of trials assessing standardized mindfulness-based stress reduction (MBSR) programs.
  • Screened for eligible studies that reported pre- and postintervention cortisol levels while rigorously controlling for the timing of cortisol collection.
  • Mindfulness-based stress reduction was associated with a significant reduction in cortisol concentrations (effect size = -0.29, 95% CI [-0.54, -0.04]).
  • Significant heterogeneity across the analyzed trials remained unexplained.

Cite This Study

Johnson et al. (2026) studied this question.

synapsesocial.com/papers/6a9d1e1f28139818eab20c6bhttps://doi.org/10.1037/hea0001636
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