Key result
Flash-freezing aortic valve homografts in the presence of dimethyl sulphoxide immediately after dissection is the most satisfactory long-term storage technique to preserve elasticity.
Why the study?
Does flash-freezing in the presence of dimethyl sulphoxide improve the elastic qualities of homograft aortic valves compared to other storage methods?
Does flash-freezing in the presence of dimethyl sulphoxide improve the elastic qualities of homograft aortic valves compared to other storage methods?
Flash-freezing homograft aortic valves with dimethyl sulphoxide immediately after dissection optimally preserves their elastic qualities for long-term storage.
Should not yet alter clinical homograft storage; hypothesis-generating for elasticity preservation in preclinical models.
Homograft aortic valves were treated and stored in different ways and then tested for elastic qualities. It appears from the findings that the most satisfactory long-term storage technique is to flash-freeze the valves in the presence of dimethyl sulphoxide immediately after dissection.
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Parker et al. (1977) studied this question. Flash-freezing aortic valve homografts in the presence of dimethyl sulphoxide immediately after dissection is the most satisfactory long-term storage technique to preserve elasticity.
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