Key result
Percutaneous mitral commissurotomy in pregnant women with severe mitral stenosis significantly increased mitral valve area from 0.78 cm2 to 2.2 cm2 (P<0.001).
Why the study?
Does percutaneous mitral commissurotomy improve hemodynamics and symptoms in pregnant females with severe mitral stenosis?
Population
27 pregnant females with severe mitral stenosis, mean age 24.9 ± 3.14 years, at 22.2 ± 4.3 weeks of…
Design
Case_series
Follow-up
1–36 months (mean 16.6 ± 7.8 months)
Authors
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May support hemodynamic benefit in pregnant severe mitral stenosis; hypothesis-generating and requires prospective validation before practice change.
Observational (n=27)
Does percutaneous mitral commissurotomy improve hemodynamics and symptoms in pregnant females with severe mitral stenosis?
Absolute Event Rate: 2.2% vs 0.78%
p-value: p=<0.001
Percutaneous mitral commissurotomy is a safe and effective procedure for severe mitral stenosis in pregnancy, significantly improving hemodynamics and symptoms.
Kalra et al. (1994) conducted an observational in Severe mitral stenosis during pregnancy (n=27). Percutaneous mitral commissurotomy vs. Baseline was evaluated on Mitral valve area (p=<0.001). Percutaneous mitral commissurotomy in pregnant women with severe mitral stenosis significantly increased mitral valve area from 0.78 cm2 to 2.2 cm2 (P<0.001).
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