Key result
No differences in embolic activity were observed when either 100% nitrogen or 95% oxygen-5% carbon dioxide gases were swept through a bubble oxygenator in an in vitro circuit.
Why the study?
Does sweeping 100% nitrogen gas reduce gaseous microemboli compared to a 95% O2-5% CO2 mixture in a bubble oxygenator?
Does sweeping 100% nitrogen gas reduce gaseous microemboli compared to a 95% O2-5% CO2 mixture in a bubble oxygenator?
Nitrogen gas does not reduce microembolic activity in bubble oxygenators compared to carbogen, and given the greater harm of nitrogen emboli, its use should be contraindicated.
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No embolic benefit of nitrogen sweep versus carbogen seen in vitro; leaves open clinical relevance and safety of nitrogen in bubble oxygenators.
J. Mandl (1977) studied Cardiopulmonary bypass. 100% Nitrogen gas vs. 95% O2-5% CO2 mixture was evaluated on Embolic activity detected by ultrasonic Doppler. No differences in embolic activity were observed when either 100% nitrogen or 95% oxygen-5% carbon dioxide gases were swept through a bubble oxygenator in an in vitro circuit.
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