Key result
Inhalation of 100% oxygen led to an exponential decrease in microembolic signal counts in 42 of 43 patients with baseline counts ≥10, suggesting nitrogen bubbles as the embolic material.
Why the study?
Does 100% oxygen ventilation reduce Doppler microemboli signals in patients with artificial heart valves?
Population
134 outpatients with artificial cardiac valves
Comparison
Noninvasive positive pressure ventilation with… vs Resting conditions
Design
Cohort
Follow-up
Acute monitoring (up to 95 minutes)
Authors
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May indicate nitrogen bubbles as embolic source in prosthetic valves; leaves open whether oxygen alters clinical events.
Does 100% oxygen ventilation reduce Doppler microemboli signals in patients with artificial heart valves?
The exponential reduction of microembolic signals during 100% oxygen inhalation suggests that nitrogen bubbles are the underlying embolic material in patients with prosthetic valves.
Georgiadis et al. (1997) studied Artificial cardiac valves (n=134). 100% oxygen inhalation vs. Resting conditions was evaluated on Microembolic signal (MES) counts. Inhalation of 100% oxygen led to an exponential decrease in microembolic signal counts in 42 of 43 patients with baseline counts ≥10, suggesting nitrogen bubbles as the embolic material.
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