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March 1, 1995Stroke

Variability of Doppler Microembolic Signal Counts in Patients With Prosthetic Cardiac Valves

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Key result

Transcranial Doppler detection of microembolic signals in patients with prosthetic cardiac valves showed no significant differences among human observers, neuronal networks, or over time (P > .05).

Why the study?

Is transcranial Doppler detection of microembolic signals reproducible in patients with mechanical prosthetic heart valves?

Population

93 patients with mechanical prosthetic heart valves

Design

Cohort, Observers blinded to previous results

Follow-up

Up to 1 year

Authors

DGDimitrios GeorgiadisHarokopio University of AthensMKManfred KapsJustus-Liebig-Universität GießenMSM. SieblerUniversity of Geneva

Discussion

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Implication

Reproducible TCD microembolic detection across observers and time; leaves open neuronal network adoption in prosthetic valve monitoring.

Study Design

Type

Observational (n=93)

Blinding

Blinded (to previous results)

Randomization

Randomized (videotapes)

Multicenter

Yes

Structured PICO

Is transcranial Doppler detection of microembolic signals reproducible in patients with mechanical prosthetic heart valves?

P
Population
93 patients with mechanical prosthetic heart valves underwent transcranial Doppler monitoring to evaluate the variability of microembolic signal detection.
E
Exposure
Transcranial Doppler monitoring for microembolic signals (evaluated by human observers and automated neuronal network)
O
Outcome
Intraobserver, interobserver, and intrasubject variability in microembolic signal countssurrogate

Main Result

p-value: p=> .05

Transcranial Doppler detection of microembolic signals in patients with mechanical prosthetic valves is highly reproducible, and automated detection using a neuronal network is feasible and reliable.

Cite This Study

Georgiadis et al. (1995) conducted an observational in Mechanical prosthetic heart valves (n=93). Transcranial Doppler monitoring for microembolic signals vs. Automated neuronal network and repeat examinations was evaluated on Differences in microembolic signal counts among observers, neuronal network, and repeat examinations (p=> .05). Transcranial Doppler detection of microembolic signals in patients with prosthetic cardiac valves showed no significant differences among human observers, neuronal networks, or over time (P > .05).

synapsesocial.com/papers/6a9ffbca8b5dbbb92fe61e9dhttps://doi.org/10.1161/01.str.26.3.439
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Correlations of Doppler Microembolic Signals in Patients With Prosthetic Cardiac Valves1998 · 45 citations
  2. 2On the origin of cerebrovascular microemboli associated with prosthetic heart valves1995 · 17 citations
  3. 3Incidence and Frequency of Cerebral Embolic Signals in Patients With a Similar Bileaflet Mechanical Heart Valve1995 · 69 citations
  4. 4Ultrasonographic Study of Micro-embolic Signal from the Heart.1997
  5. 5Solid Cerebral Microemboli and Cerebrovascular Symptoms in Patients With Prosthetic Heart Valves2008 · 20 citations