Key result
Doppler microembolic signals varied by prosthetic valve type but showed no significant difference in prevalence between neurologically symptomatic and asymptomatic patients (63% vs 69%, P>0.05).
Why the study?
Do Doppler microembolic signals correlate with neurological complications in patients with prosthetic cardiac valves?
Population
580 patients with prosthetic cardiac valves, including a subset of 369 patients carrying the valve implant…
Design
Cross-sectional
Authors
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Microembolic signals lack symptom correlation and should not yet change practice; leaves open their investigation as valve-type-specific biomarkers.
Observational (n=580)
Yes
Do Doppler microembolic signals correlate with neurological complications in patients with prosthetic cardiac valves?
Absolute Event Rate: 63% vs 69%
p-value: p=>.05
Doppler microembolic signals in patients with prosthetic cardiac valves depend on valve type but do not correlate with neurological symptoms, suggesting they lack direct clinical significance.
Sliwka et al. (1998) conducted an observational in Prosthetic cardiac valves (n=580). Prosthetic cardiac valves vs. Different valve types was evaluated on Microembolic signal (MES) prevalence in neurologically symptomatic versus asymptomatic patients (p=>.05). Doppler microembolic signals varied by prosthetic valve type but showed no significant difference in prevalence between neurologically symptomatic and asymptomatic patients (63% vs 69%, P>0.05).