February 1, 1997Stroke

Clinically Silent Microemboli in Patients With Artificial Prosthetic Aortic Valves Are Predominantly Gaseous and Not Solid

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Why the study?

Does inspiration of 100% oxygen reduce microembolic signals in patients with prosthetic aortic valves?

Population

5 patients with prosthetic aortic valves

Comparison

Inspiration of 100% oxygen through a facial mask vs Baseline (implied)

Design

Case_series

Authors

MKManfred KapsJustus-Liebig-Universität Gießen JHJochen HansenDiakonhjemmet Hospital MWM. WeiherFriedrich-Ebert-Krankenhaus

Discussion

Member takes

Implication

Supports gaseous MES etiology in prosthetic valves; hypothesis-generating for oxygen, needs controlled trials before any clinical use.

Structured PICO

Does inspiration of 100% oxygen reduce microembolic signals in patients with prosthetic aortic valves?

Population

5 patients with prosthetic aortic valves

Intervention

Inspiration of 100% oxygen through a facial mask (one patient under hyperbaric conditions)

Comparator

Baseline (implied)

Outcome

Number of microembolic signals (MES) measured by transcranial Doppler ultrasoundsurrogate

Microembolic signals observed after prosthetic heart valve implantation are predominantly gaseous, as their occurrence is dependent on oxygen partial pressure.

Cite This Study

Kaps et al. (1997) studied this question.

synapsesocial.com/papers/6a954792cd304312aafa763c https://doi.org/10.1161/01.str.28.2.322

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