Key result
Myelin-free axons isolated from rat CNS contained 15.2% lipid on a dry weight basis, composed of 19.4% cholesterol, 56.9% phospholipid, and 23.7% galactolipid.
Population
Myelin-free axons isolated from rat central nervous system
Design
Preclinical
Authors
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Leaves open clinical translation from rat axons; extends evidence that galactolipids are intrinsic axonal components.
The study details the specific lipid composition of myelin-free axons isolated from rat CNS, demonstrating that axonal galactolipid is not due to myelin contamination.
Vries et al. (1976) studied this question. Isolation of myelin-free axons was evaluated on Lipid composition. Myelin-free axons isolated from rat CNS contained 15.2% lipid on a dry weight basis, composed of 19.4% cholesterol, 56.9% phospholipid, and 23.7% galactolipid.
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