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January 1, 1976Journal of Neurochemistry

Gangliosides of Peripheral Nerve Myelin

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Population

Myelin obtained from three types of peripheral nerve: bovine spinal roots, bovine sciatic nerve, and human…

Design

Preclinical

Discussion

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Implication

Highlights PNS-CNS myelin differences in animals; extends ganglioside mapping but leaves open human neuropathy relevance.

Structured PICO

P
Population
Myelin obtained from three types of peripheral nerve: bovine spinal roots, bovine sciatic nerve, and human sciatic nerve
I
Intervention
Isolation and biochemical analysis of gangliosides
O
Outcome
Ganglioside composition, yield, and structural characteristics

The study characterizes the ganglioside composition of peripheral nerve myelin, demonstrating that it differs significantly from central nervous system myelin.

Cite This Study

A 1976 study studied this question.

synapsesocial.com/papers/6a87ed2bf8efd6d7e4fb2282https://doi.org/10.1111/j.1471-4159.1976.tb04451.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1GANGLIOSIDES OF HUMAN MYELIN: SIALOSYLGALACTOSYLCERAMIDE (G7) AS A MAJOR COMPONENT1973 · 534 citations
  2. 2Gangliosides of human, bovine, and rabbit plasma1972 · 353 citations
  3. 3FORMATION AND TURNOVER OF MYELIN GANGLIOSIDE*1970 · 66 citations
  4. 4A source of contamination in the ultramicro analysis of methyl esters of fatty acids by gas-liquid chromatography1964 · 31 citations
  5. 5A MODIFIED PROCEDURE FOR THE ANALYSIS OF MIXTURES OF TISSUE GANGLIOSIDES11969 · 72 citations