Key result
A higher visceral adiposity index was independently associated with increased odds of lung function impairment, particularly in women, where each 10% increase in VAI was associated with a 16.1% higher odds of FVC impairment (OR 1.161).
Why the study?
Visceral adiposity impacts lung function, but the relationship between the visceral adiposity index (VAI) and lung function had not been investigated.
Is the visceral adiposity index associated with lung function impairment in middle-aged and elderly adults?
Cross-Sectional (n=1,786)
Is the visceral adiposity index associated with lung function impairment in middle-aged and elderly adults?
Odds Ratio: 1.161 (95% CI 1.07876–1.253)
p-value: p=<0.001
The visceral adiposity index is independently associated with lung function impairment, particularly in women, suggesting its potential utility as a simple screening tool for respiratory risk.
VAI-lung function link is hypothesis-generating; prospective validation needed before any clinical or predictive use.
Background: The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the visceral adiposity index (VAI) has been proposed as a visceral fat distribution and dysfunction marker. However, the relationship between the VAI and lung function has not been investigated. The objective of the study was to analyze the association between the VAI and lung function and evaluate the potential of VAI as a predictor of lung function. Methods: We collected data from a population-based study of 1786 subjects aged 40 years or older. All subjects completed a questionnaire and underwent anthropometric measurements and laboratory tests. Linear and logistic regression models were developed to assess the association between the VAI and lung function. Results: The VAI was inversely related to FVC%predicted in men and negatively associated with both FVC%predicted and FEV1%predicted in women. In the linear regression analysis, the decrease in FVC%predicted associated with each 10% increase in the VAI was 1.127% in men and 1.943% in women; the decrease in FEV1%predicted associated with each 10% increase in the VAI was 0.663% in men and 1.738% in women. Further regression analysis revealed that the VAI was positively correlated with FVC and FEV1 impairment in women. Conclusions: We were the first to show a clear correlation between the VAI and lung function impairment in the Chinese population. The VAI could be a simple and reliable approach in daily practice, and individuals, especially women with a high VAI, should receive additional screening and preventive interventions for respiratory disease.
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He et al. (2020) conducted a cross-sectional in Lung function impairment (n=1,786). Visceral adiposity index (VAI) vs. Lower VAI was evaluated on Forced vital capacity (FVC) impairment in women (per 10% increase in VAI) (OR 1.161, 95% CI 1.07876-1.253, p=<0.001). A higher visceral adiposity index was independently associated with increased odds of lung function impairment, particularly in women, where each 10% increase in VAI was associated with a 16.1% higher odds of FVC impairment (OR 1.161).
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