Key result
In 100 autopsy cases of lung cancer, the great vessels, pericardium, and heart were invaded in 38, 27, and 7 cases respectively, indicating a centrifugal pattern of lymphatic spread.
Population
100 autopsy cases of lung cancer from the University of Glasgow
Design
Case_series
Authors
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Autopsy data on lung cancer cardiac invasion is hypothesis-generating; leaves open relevance to antemortem staging or imaging.
Observational (n=100)
No
Autopsy data of lung cancer patients demonstrates that metastasis to the heart, pericardium, and great vessels occurs in a centrifugal pattern, primarily driven by lymphatic spread rather than direct extension.
Wilson IB Onuigbo (1974) conducted an observational in Lung cancer (n=100). Lung cancer was evaluated on Invasion of great vessels, pericardium, and heart. In 100 autopsy cases of lung cancer, the great vessels, pericardium, and heart were invaded in 38, 27, and 7 cases respectively, indicating a centrifugal pattern of lymphatic spread.
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