Key result
Arterial tumor emboli were identified in 20 of 23 cases of pulmonary lymphangitic carcinomatosis, suggesting the pathogenic mechanism is primarily vascular embolization rather than retrograde spread.
Observational (n=23)
The pathogenic mechanism of pulmonary lymphangitic carcinomatosis may primarily be vascular embolization rather than retrograde spread from central lymph nodes.
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Should not alter management of pulmonary lymphangitic carcinomatosis; leaves open dominant mechanism for prospective validation.
Janower et al. (1971) conducted an observational in Pulmonary lymphangitic carcinomatosis (n=23). Pulmonary lymphangitic carcinomatosis was evaluated on Radiologic-pathologic correlation and presence of arterial tumor emboli vs lymph node involvement. Arterial tumor emboli were identified in 20 of 23 cases of pulmonary lymphangitic carcinomatosis, suggesting the pathogenic mechanism is primarily vascular embolization rather than retrograde spread.
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