Key result
Percutaneous mitral balloon valvuloplasty in pregnant women with mitral stenosis increased mean mitral valve area from 1.17 to 2.06 cm2.
Why the study?
Does percutaneous mitral balloon valvuloplasty improve hemodynamics and pregnancy outcomes in pregnant women with mitral stenosis?
Observational (n=44)
Does percutaneous mitral balloon valvuloplasty improve hemodynamics and pregnancy outcomes in pregnant women with mitral stenosis?
Percutaneous mitral balloon valvuloplasty is a safe and effective procedure for pregnant women with mitral stenosis, significantly improving valve hemodynamics and allowing the majority to reach term delivery.
Answers are grounded in this paper and cite their sources.
Supports PMBV consideration in pregnant MS; extends observational data but leaves open need for controlled outcome trials.
Forty-four consecutive pregnant patients with mitral stenosis were submitted to percutaneous mitral valvuloplasty (PMV) over a period of 12 years. The mean age was 28 +/- 6 years and the mean gestational age was 23 +/- 6 weeks. The mean mitral valve area had a significant increase from 1.17 +/- 0.26 to 2.06 +/- 0.41 cm(2) (P = 0.0000). The mean mitral valve gradient decreased from 16.22 +/- 5.55 to 7.94 +/- 3.75 mm Hg (P = 0.0001). The procedure was performed successfully in 95% of the patients and there were no major complications. Concerning labor and delivery, we evaluated 37 patients. Thirty patients (81%) reached term and delivered normal infants. Seven patients (18.9%) delivered prematurely, resulting in two fetal death; one patient delivered a stillborn. We concluded that PMV is a safe procedure for the treatment of mitral stenosis in pregnant patients, providing significant symptomatic relief and better clinical conditions for labor and delivery.
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Nercolini et al. (2002) conducted an observational in mitral stenosis in pregnancy (n=44). Percutaneous mitral balloon valvuloplasty vs. Pre-procedure baseline was evaluated on mitral valve area (p=0.0000). Percutaneous mitral balloon valvuloplasty in pregnant women with mitral stenosis increased mean mitral valve area from 1.17 to 2.06 cm2.
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