Key result
Closed mitral valvotomy during pregnancy for severe refractory mitral stenosis resulted in clinical improvement in all 8 patients, with no mortality or major morbidity.
Why the study?
Does closed mitral valvotomy improve clinical outcomes in pregnant women with severe mitral stenosis refractory to medical therapy?
Observational (n=8)
Does closed mitral valvotomy improve clinical outcomes in pregnant women with severe mitral stenosis refractory to medical therapy?
Closed mitral valvotomy is a safe, feasible, and cost-effective alternative for pregnant women with severe mitral stenosis in resource-limited settings where balloon mitral valvotomy is not affordable.
May support closed mitral valvotomy in refractory pregnancy cases; hypothesis-generating and should not yet change practice.
OBJECTIVE: To study the feasibility and benefits of closed mitral valvotomy (CMV) during pregnancy. DESIGN: Prospective study from 2000 through 2003 to study the effect on maternal condition and perinatal outcome of closed mitral valvotomy during pregnancy were evaluated. METHODS: Eight pregnant women with severe mitral stenosis refractory to medical therapy had closed mitral valvotomy at different stages of pregnancy (one during labor). RESULTS: All patients improved clinically (according to the New York Heart Association classification), and the mitral valve area increased. There was no mortality or major morbidity. CONCLUSION: Closed mitral valvotomy offers excellent results and is cost effective during pregnancy. It is still the procedure of choice in poor countries when balloon mitral valvotomy (BMV) is not affordable.
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Aggarwal et al. (2004) conducted an observational in Severe mitral stenosis (n=8). Closed mitral valvotomy was evaluated on Clinical improvement (NYHA classification) and mortality/major morbidity. Closed mitral valvotomy during pregnancy for severe refractory mitral stenosis resulted in clinical improvement in all 8 patients, with no mortality or major morbidity.
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