Key result
A 22-year-old male bodybuilder developed rhabdomyolysis-induced acute kidney injury following ibuprofen use and strenuous exercise, which fully resolved after seven hemodialysis sessions.
Case Report (n=1)
No
This case highlights the risk of severe rhabdomyolysis-induced AKI requiring dialysis in young athletes combining intense physical exertion with NSAID use.
This is the authors' abstract. We don't add key points for this paper.
Acute kidney injury (AKI) is a serious medical condition that can have many causes, including rhabdomyolysis. Rhabdomyolysis is the breakdown of muscle tissue that can lead to the release of muscle fiber contents into the bloodstream. This can cause serious damage to the kidneys, leading to AKI. In this case, a young bodybuilder was diagnosed with rhabdomyolysis induced by AKI after consuming Ibuprofen for a casual fever. The etiology of AKI in rhabdomyolysis is complex, with multiple factors contributing to the development of the condition. These include muscle trauma, dehydration, infection, and drug toxicity. In this case, Ibuprofen may have contributed to the development of AKI, as it can cause kidney damage when taken in large doses. Additionally, the bodybuilder's physical activity may have contributed to the development of rhabdomyolysis, as intense exercise can cause muscle damage. Treatment for AKI in rhabdomyolysis patients typically involves aggressive fluid resuscitation, electrolyte replacement, and dialysis if necessary. Additionally, the underlying cause of the rhabdomyolysis must be identified and treated. In this case, the patient should be monitored closely for any signs of kidney damage, and the Ibuprofen should be discontinued. In conclusion, this is a case of a relatively common presentation with uncommon circumstances. It is crucial to have a heightened understanding of the likelihood of AKI in patients with rhabdomyolysis and the impact of drug toxicity in exacerbating the condition. Early diagnosis and treatment are essential for the successful management of AKI.
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Warrants caution on NSAID use during intense exercise in young athletes; leaves open need for prospective incidence and prevention studies.
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Alikutty et al. (2023) conducted a case report in Rhabdomyolysis-Induced Acute Kidney Injury (n=1). Ibuprofen and strenuous exercise was evaluated on Clinical recovery and normalization of renal function markers. A 22-year-old male bodybuilder developed rhabdomyolysis-induced acute kidney injury following ibuprofen use and strenuous exercise, which fully resolved after seven hemodialysis sessions.
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