Key result
Acute kidney injury secondary to rhabdomyolysis resolved in 100% of the 16 patients following conservative management or dialysis.
Why the study?
Rhabdomyolysis is an uncommon cause of acute kidney injury with diverse causes and pathogenic mechanisms requiring characterization in local cases.
Observational (n=16)
No
Acute kidney injury secondary to rhabdomyolysis can be effectively managed with fluid replacement or dialysis, leading to resolution in all cases.
Answers are grounded in this paper and cite their sources.
Small series shows AKI resolution with standard care in rhabdomyolysis; leaves open confirmation in larger prospective studies.
Rhabdomyolysis constitutes an uncommon cause of acute kidney injury (AKI). A large variety of causes with different pathogenic mechanisms may involve skeletal muscles resulting in rhabdomyolysis with or without acute kidney injury. Crush syndrome and unaccustomed physical exertion are the most common causes of rhabdomyolysis. This study reports local cases of AKI secondary to rhabdomyolysis that presented to a tertiary care centre over a period of four years. Most of them were males and belonged to younger age group. Muscle enzyme creatine phosphokinase level was raised in all patients, while myoglobinuria was detected only in one patient. Most of the patients (10/16) were managed conservatively with fluid replacement; and some of them (6/16) needed dialysis. AKI was resolved in all the patients after a variable period of time.
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Ahmad et al. (2021) conducted an observational in Acute kidney injury secondary to rhabdomyolysis (n=16). Rhabdomyolysis was evaluated on Resolution of AKI. Acute kidney injury secondary to rhabdomyolysis resolved in 100% of the 16 patients following conservative management or dialysis.
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