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Characterize the chemical and immunological properties of the protective antigen isolated from crude extracts of Bacillus anthracis skin lesions.

Studies on Infection with Bacillus Anthracis: III. Chemical and Immunological Properties of the Protective Antigen in Crude Extracts of Skin Lesions of B. Anthracis

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Characterize the chemical and immunological properties of the protective antigen isolated from crude extracts of Bacillus anthracis skin lesions.
Extracted crude tissue material from cutaneous lesions caused by Bacillus anthracis infection.
Assayed extracted fractions to determine chemical stability, composition, and immunological activity.
Confirmed the presence of viable protective antigen components in crude extracts derived from infected skin lesions.
Characterized baseline chemical stability and specific immunological reactivity associated with the protective anthrax antigen.

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Laboratory analysis characterizes protective antigen in anthrax skin lesions, indicating mechanisms vital for developing protective vaccines.

Watson et al. (1947) studied this question.

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Laboratory analysis characterizes protective antigen in anthrax skin lesions, indicating mechanisms vital for developing protective vaccines.