Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 15, 2011Gynecological Endocrinology

Association between serum adipocyte factor level and insulin resistance in polycystic ovarian syndrome

View Full Paper
Ask AI
Bookmark
Share

Key result

Insulin resistance in women with polycystic ovary syndrome was associated with significantly lower serum adiponectin levels compared to those without insulin resistance (P < 0.05).

Why the study?

Are serum adipocytokine levels associated with insulin resistance in patients with polycystic ovary syndrome?

Population

61 patients with polycystic ovary syndrome (PCOS)

Comparison

Insulin resistance (IR) vs Non-insulin resistance (non-IR)

Design

Cross-sectional

Authors

QWQiushi WangJinan UniversityTGTao GuoWeifang Medical UniversityTYTao YuWeifang Medical University

Discussion

Loading...

Member takes

Implication

May mark insulin resistance in PCOS; hypothesis-generating cross-sectional link leaves causality and therapeutic implications open.

Study Design

Type

Observational (n=61)

Structured PICO

Are serum adipocytokine levels associated with insulin resistance in patients with polycystic ovary syndrome?

P
Population
61 women with polycystic ovary syndrome, divided into insulin resistance (n=31) and non-insulin resistance (n=30) groups based on HOMA.
E
Exposure
Insulin resistance (IR)
C
Comparator
Non-insulin resistance (non-IR)
O
Outcome
Serum levels of adipocytokines (adiponectin, resistin, leptin, and leptin receptor)surrogate

Main Result

p-value: p=<0.05

Lower serum adiponectin levels are associated with insulin resistance in women with polycystic ovary syndrome.

Cite This Study

Wang et al. (2011) conducted an observational in Polycystic ovary syndrome (PCOS) (n=61). Insulin resistance vs. Non-insulin resistance was evaluated on Serum adiponectin level (p=<0.05). Insulin resistance in women with polycystic ovary syndrome was associated with significantly lower serum adiponectin levels compared to those without insulin resistance (P < 0.05).

synapsesocial.com/papers/6a9d7db9a07850bc91a4cb32https://doi.org/10.3109/09513590.2011.569597
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adiponectin Levels in Women with Polycystic Ovary Syndrome2003 · 173 citations
  2. 2Rosiglitazone treatment increases plasma levels of adiponectin and decreases levels of resistin in overweight women with PCOS: a randomized placebo-controlled study2007 · 89 citations
  3. 3Adiponectin - Its Role in Metabolism and Beyond2002 · 293 citations
  4. 4Adiponectin levels in women with polycystic ovary syndrome: a systematic review and a meta-analysis2009 · 258 citations