Key result
A review of >30 patents on sodium channel blockers from 2010 to 2014 highlights continuous discovery efforts, though developing subtype-selective compounds remains a major hurdle.
Design
Review
Authors
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Sustained patent activity signals ongoing innovation in sodium channel blockers; leaves open whether subtype selectivity can be achieved for clinical gains.
This patent review highlights the ongoing effort to discover new sodium channel blockers, emphasizing the need for subtype-selective compounds to improve efficacy and tolerability.
Zuliani et al. (2014) reported a review. Sodium channel blockers was evaluated. A review of >30 patents on sodium channel blockers from 2010 to 2014 highlights continuous discovery efforts, though developing subtype-selective compounds remains a major hurdle.
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