Recent Advances in the Treatment of Pellagra and Associated Deficiencies

Article1 May 1939RECENT ADVANCES IN THE TREATMENT OF PELLAGRA AND ASSOCIATED DEFICIENCIESTOM D. SPIES, M.D., WILLIAM B. BEAN, M.D., WILLIAM F. ASHE, M.D.TOM D. SPIES, M.D.Search for more papers by this author, WILLIAM B. BEAN, M.D.Search for more papers by this author, WILLIAM F. ASHE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-11-1830 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1735 Gaspar Casal, a Spanish physician, first described pellagra and shrewdly pointed out that this disease is related to an inadequate diet.1That diet was the controlling factor in the etiology of the disease was not suggested again until the work of Goldberger, Waring and Willets2in 1915. During the next two decades, the full significance of diet in the development of pellagra gradually became evident because of the frequent association of the disease with faulty nutrition. Later, the administration of a high caloric diet, rich in protein and vitamins, supplemented with large amounts of antipellagric materials such as...Bibliography1. CASAL G: Historia natural y medica de el principado de Asturias, Obra post-huma del Doctor D. G. Casal, Medico de Su Magnestad y su Protomedicin de Castilla, Madrid, 1762. Google Scholar2. GOLDBERGERWARINGWILLETS JCHDG: The prevention of pellagra, Pub. Health Rep., 1915, xxx, 3117. CrossrefGoogle Scholar3. SPIES TD: The treatment of pellagra, Jr. Am. Med. Assoc., 1935, civ, 1377. CrossrefGoogle Scholar4. SPIESCHINNMCLESTER TDABJB: Severe endemic pellagra; a clinical study of fifty cases with special emphasis on therapy, Jr. Am. Med. Assoc., 1937, cviii, 853. CrossrefGoogle Scholar5. 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SEBRELLBUTLER WHRE: Riboflavin deficiency in man (a preliminary report), Pub. Health Rep., 1938, liii, 2282. CrossrefGoogle Scholar37. SPIESGRANT TDJM: Unpublished observations. Google Scholar38. EMMERIE A: Determination and excretion of flavins in normal human urine, Nature, 1936, cxxxviii, 164. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cincinnati, Ohio*Read before the American College of Physicians, New Orleans, March 29, 1939.From the Department of Internal Medicine, University of Cincinnati College of Medicine, and the Cincinnati General Hospital, Cincinnati, Ohio; and the Hillman Hospital, Birmingham, Alabama. These studies were aided by grants from the David May Fund, the Busch Fund, and the Fleischmann Endowment Fund of the University of Cincinnati College of Medicine.†Recipient of the John Phillips Memorial Medal of the American College of Physicians for 1938-39. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExpression, Localization, and Biochemical Characterization of Nicotinamide Mononucleotide Adenylyltransferase 2Chapter 30 Historical aspects of the major neurological vitamin deficiency disorders: the water-soluble B vitaminsPellagra: A clue as to why energy failure causes diseases?The Relationship of Pellagra to Corn and the Low Availability of Niacin in CerealsClinical Significance of Riboflavin DeficiencyRiboflavin DeficiencyExperimental Dietary and Antagonist-Induced Human Riboflavin DeficiencyReversible pellagra-like encephalopathy with ethionamide and cycloserineNutrition Assessment in Chronic Kidney DiseaseHautveränderungen bei Störungen des VitaminstoffwechselsHuman Requirements for Vitamin B6The Metabolic Functions of Vitamin B 12Riboflavin, Light, and the Growth of PlantsA Comparison of Dental Caries Activity in Malnourished and Well-Nourished PatientsThe Natural Occurrence of Riboflavin Deficiency in the Eyes of DogsPharmacological Interactions of Cobra Venom and ThiamineThe treatment of sprue with vitamin B2 and its bearing upon the aetiology of this diseaseChemical Determination of Nicotinic AcidTRENCH MOUTHRIBOFLAVIN CONTENT OF SOME COMMON VEGETABLES AND FRUITSA survey of the state of nutrition with respect to vitamin C in a southern pediatric clinic 1 May 1939Volume 12, Issue 11Page: 1830-1844KeywordsDietEtiologyHospital medicineNutritionProteinsVitamins ePublished: 1 December 2008 Issue Published: 1 May 1939 PDF downloadLoading ...