Key result
Prolonged cumulative cardiopulmonary bypass time (>180 minutes) significantly predicted mortality, while CPB/graft time >56 minutes indirectly increased mortality risk via complications.
Why the study?
Does prolonged cardiopulmonary bypass time increase the risk of mortality and postoperative complications in patients undergoing isolated on-pump CABG?
Population
1,960 patients who had undergone isolated on-pump coronary artery bypass grafting (CABG) from 2009 to 2014
Comparison
Prolonged cumulative cardiopulmonary bypass time… vs Shorter CPB times
Design
Cohort
Follow-up
short- and intermediate-term
Authors
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Keeping cumulative CPB time below 180 minutes and CPB/graft time below 56 minutes may minimize adverse postoperative outcomes, including mortality, in patients undergoing on-pump CABG.
Cohort (n=1,960)
Does prolonged cardiopulmonary bypass time increase the risk of mortality and postoperative complications in patients undergoing isolated on-pump CABG?
Keeping cumulative CPB time below 180 minutes and CPB/graft time below 56 minutes may minimize adverse postoperative outcomes, including mortality, in patients undergoing on-pump CABG.
Madhavan et al. (2018) conducted a cohort in Isolated on-pump CABG (n=1,960). Prolonged cardiopulmonary bypass (CPB) time vs. Shorter CPB time was evaluated on Mortality and postoperative clinical events. Prolonged cumulative cardiopulmonary bypass time (>180 minutes) significantly predicted mortality, while CPB/graft time >56 minutes indirectly increased mortality risk via complications.
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