Key result
Each additional 15 minutes of CABG operating room time is linked to higher morbidity and mortality.
Why the study?
While prolonged CPB time during CABG is associated with poor outcomes, the association of other operating room times is less understood.
Does prolonged operating room time (including non-surgical time) increase morbidity, mortality, and resource utilization in patients undergoing primary CABG?
Cohort (n=29,206)
Yes
Does prolonged operating room time (including non-surgical time) increase morbidity, mortality, and resource utilization in patients undergoing primary CABG?
Answers are grounded in this paper and cite their sources.
Prolonged operating room times, including non-surgical times, are independently associated with increased morbidity, mortality, and healthcare costs following primary CABG.
OBJECTIVES: Prolonged cardiopulmonary bypass (CPB) time during coronary artery bypass grafting (CABG) is associated with poor outcomes, however, the association of other operating room (OR) times is less understood. We studied the impact of OR times on outcomes and resource utilization after CABG. METHODS: Patients undergoing isolated primary CABG from a large multicentre regional collaborative were analysed. The impact of risk-adjusted total OR, surgery, non-surgery, CPB, and off-CPB times on morbidity, extubation time, ICU and hospital length of stay (LOS), cost, and mortality, was studied. Multivariable regressions were performed adjusting for STS predicted risk of morbidity or mortality, intraoperative blood transfusion, CPB time, cross-clamp time, presence of a cardiothoracic surgery fellowship program, and year of surgery. Our adjustment accounted for patient and intraoperative factors that contribute to complexity and intraoperative course of surgery. All models incorporated centre as a random effect to account for hospital-level variations. RESULTS: Among 29 206 patients (mean age 64.8 years, 76% male), median OR, surgery, non-surgery, and CPB times were 308, 235, 72, and 141 minutes, respectively. Longer surgery times were significantly associated with complications, prolonged ventilation, longer ICU and hospital LOS, and mortality. Similarly, increasing non-surgery OR time was significantly associated with worse outcomes, including longer LOS and complications. Each additional 15 minutes in the OR was associated with increased odds of complications, mortality, and cost. CONCLUSIONS: Longer non-surgical OR times are associated with adverse outcomes and increased cost. Improving OR efficiency may contribute to better patient outcomes.
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Moheb et al. (2025) conducted a cohort in isolated primary CABG (n=29,206). Longer operating room times vs. Shorter operating room times was evaluated on morbidity, extubation time, ICU and hospital length of stay, cost, and mortality.
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