Reports a small passive wireless humidity monitoring system (HMS) for continuous remote monitoring of humidity changes inside miniature hermetic packages, presents its application in determining hermeticity of an implantable biomedical package, and presents long-term performance results obtained from packages implanted in guinea pigs. This 7/spl times/1.2/spl times/1.5 mm/sup 3/ system consists of a high-sensitivity capacitive humidity sensor that forms an LC tank circuit together with a hybrid coil wound around a ferrite substrate. The resonant frequency of the circuit changes when the humidity sensor capacitance changes in response to changes in humidity. The HMS can resolve humidity changes of /spl plusmn/2.5% RH over a 2-cm range. The resolution is sufficient enough to monitor internal package humidity for either in vitro or in vivo testing.
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Harpster et al. (2002) studied this question.
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