Key result
Emergency Cesarean section with administration of oxytocin and tranexamic acid successfully preserved the uterus and stabilized the hemodynamics of a 27-year-old woman with severe Couvelaire syndrome.
Why the study?
Couvelaire syndrome is a rare pregnancy complication, and reporting a grave case alongside a literature review aims to support clinical pathways for early diagnosis and treatment to prevent feto-maternal consequences.
Case Report (n=1)
Prompt diagnosis and individualized management of Couvelaire syndrome with urgent Cesarean section and uterine-preserving techniques can lead to successful maternal and fetal outcomes.
May support uterine preservation in severe Couvelaire syndrome; hypothesis-generating and requires prospective validation before practice change.
Introduction. Couvelaire syndrome is a rare complication of pregnancy involving the placenta and the uterine wall. It is caused by placental abruption, preeclampsia, or other disorders that compromise the blood supply to the placenta. Diagnosis is typically made through history, clinical evaluation, and ultrasound. This study aims to report a grave case of Couvelaire syndrome complemented by presenting a review of the relevant literature, to aid the meaning of a clinical path, as well as early and adequate diagnosis and treatment of Couvelaire syndrome, to prevent feto-maternal consequences. The treatment of Couvelaire syndrome depends on the severity of the condition and the well-being of both the mother and the fetus. If the condition is severe and poses a risk to the mother or fetus, immediate delivery may be recommended, mainly with urgent Cesarean section in general endotracheal anesthesia. If there is significant blood loss leading to a decrease in hemoglobin levels, blood transfusions may be necessary to restore normal blood volume and oxygen-carrying capacity. Part of the general treatment plan should also be the management of the underlying cause of placental abruption, for example, in cases of preeclampsia, medications are prescribed to control blood pressure and prevent seizures.
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Gashi et al. (2024) conducted a case report in Couvelaire Syndrome (n=1). Emergency Cesarean section and medical management (oxytocin, tranexamic acid) was evaluated on Maternal and fetal survival and uterine preservation. Emergency Cesarean section with administration of oxytocin and tranexamic acid successfully preserved the uterus and stabilized the hemodynamics of a 27-year-old woman with severe Couvelaire syndrome.
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