Key result
Two monoclonal antibodies, 1C8 and 2C10, were generated against the S1 subunit of avian infectious bronchitis virus, demonstrating cross-reactivity across five genotypes and neutralizing activity.
The generated anti-S1 monoclonal antibodies 1C8 and 2C10 demonstrate cross-reactivity and neutralizing activity against avian infectious bronchitis virus, providing potential tools for immunodiagnosis and immunotherapy in poultry.
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May support IBV immunodiagnostics in poultry; leaves open translation from animal data to field use.
Zou et al. (2015) studied Avian infectious bronchitis. Anti-S1 monoclonal antibodies (1C8 and 2C10) was evaluated on Neutralization titer against Sczy3. Two monoclonal antibodies, 1C8 and 2C10, were generated against the S1 subunit of avian infectious bronchitis virus, demonstrating cross-reactivity across five genotypes and neutralizing activity.
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