Key result
A left-ventricular dynamic model requires the inclusion of elastance, resistance, series-elastance, and deactivation effects to accurately describe and predict left ventricular pressure.
Population
Rabbit left ventricle
Comparison
Three-element time-varying model with… vs Three-element model without deactivation effect
Design
Preclinical
Authors
Loading...
Refines animal LV pressure modeling; leaves open human validation before clinical use.
Computational modeling of the left ventricle requires the inclusion of a deactivation effect alongside elastance and resistance to accurately predict ventricular pressure.
Wijkstra et al. (1991) studied Left ventricular dynamics. Simulation model with deactivation effect vs. Simulation model without deactivation effect was evaluated on Left ventricular pressure prediction. A left-ventricular dynamic model requires the inclusion of elastance, resistance, series-elastance, and deactivation effects to accurately describe and predict left ventricular pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: