Key result
A 35-year-old woman with double outlet left ventricle and a prosthetic valve successfully delivered a healthy infant following careful anticoagulant management with heparin and warfarin.
Why the study?
Does a carefully managed anticoagulation protocol substituting heparin for warfarin during high-risk periods allow for successful pregnancy in a patient with double outlet left ventricle and a mechanical prosthetic valve?
Case Report (n=1)
No
Does a carefully managed anticoagulation protocol substituting heparin for warfarin during high-risk periods allow for successful pregnancy in a patient with double outlet left ventricle and a mechanical prosthetic valve?
Successful pregnancy is possible in patients with double outlet left ventricle after a Rastelli operation with a mechanical valve using a carefully managed anticoagulation protocol substituting heparin for warfarin during high-risk periods.
Supports feasibility of managed anticoagulation for pregnancy in complex CHD with mechanical valves; leaves open need for prospective data before practice change.
A woman with double outlet left ventricle (DOLV) had undergone a Rastelli operation using a prosthetic Björk Shiley valve and who was receiving anticoagulant drug delivered a healthy male infant. Oral warfarin was replaced by heparin from the 5th to the 13th week of gestation and for the last 5 weeks of gestation. Successful pregnancy in patients with DOLV after a Rastelli operation using a prosthetic valve is possible with careful maintenance.
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Fukuda et al. (2004) conducted a case report in Double outlet left ventricle (DOLV) after Rastelli operation with a prosthetic valve in pregnancy (n=1). Anticoagulant management (heparin substituted for warfarin during weeks 5-13 and near term) was evaluated on Successful pregnancy and delivery. A 35-year-old woman with double outlet left ventricle and a prosthetic valve successfully delivered a healthy infant following careful anticoagulant management with heparin and warfarin.
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