Why the study?
Standardizing an approach to anticoagulation during pregnancy in women with prosthetic heart valves is challenging and not always possible in complex cardiac cases.
Highlights the need for individualized anticoagulation strategies and shared decision-making in pregnant patients with complex congenital heart disease and mechanical valves.
May guide individualized anticoagulation via shared decisions in complex pregnant valve patients; leaves open need for prospective safety data.
This article discusses the challenges of supporting a successful pregnancy in a woman with multiple prosthetic heart valves and a complicated cardiac history, from both the patient and provider perspective. The patient is a 29-year-old female with truncus arteriosus type I with initial neonatal VSD closure and right ventricular to pulmonary artery conduit. At the age of 13, she subsequently required truncal and pulmonary valve replacements with mechanical prostheses. Standardizing an approach to anticoagulation in pregnancy in women with prosthetic heart valves is not always possible. Her story demonstrates the importance of an innovative approach to unique cases; by extrapolating what is known about pregnancy and prosthetic heart valves, cardiologists can provide the best outcomes. Simultaneously, non-directive counseling is essential throughout this period to engage the patient in shared decision-making when balancing risks and benefits of each approach to anticoagulation.
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Ledingham et al. (2022) studied this question.
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