Key result
Body mass index was not significantly associated with 30-day mortality after coronary artery bypass grafting, but was an independent predictor of postoperative pulmonary complications (OR 1.6).
Why the study?
Does body mass index affect early mortality and morbidity in patients undergoing isolated coronary artery bypass grafting?
Cohort (n=1,673)
No
Does body mass index affect early mortality and morbidity in patients undergoing isolated coronary artery bypass grafting?
p-value: p=0.229
Body mass index is an independent predictor of post-CABG pulmonary complications but not of early post-CABG mortality.
Does not support BMI-based changes to CABG candidacy or mortality risk assessment; leaves open targeted strategies to reduce pulmonary complications in higher-BMI patients.
Background: This study aims to investigate the effects of body mass index (BMI) on early surgical outcomes of coronary artery bypass grafting (CABG). Methods: Between August 2007 and March 2011, a total of 1,673 consecutive patients (1,209 males, 464 females; mean age 58.6±9.9 years; range 21 to 87 years) who underwent isolated CABG at Shariati Hospital, Tehran, Iran were retrospectively analyzed. The patients were classified into four groups based on the BMI values: underweight (BMI ≤19 kg/m2, n=55), normal/overweight (BMI 20-29 kg/m2, n=523), obese (BMI 30-39 kg/m2, n=739) and morbidly obese (BMI ≥40 kg/m2, n=356). Preoperative characteristics were compared among the four groups. Effects of BMI on postoperative mortality and morbidity were evaluated using the stepwise multivariate logistic regression analysis. Results: There was no significant difference in the mortality rate among the groups. Intra-aortic balloon pump (IABP) was the only independent predictor of postoperative mortality in the multivariate logistic regression analysis (OR=20.5, 95% CI=8.6-50.5; p
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Jamshid Bagheri (2014) conducted a cohort in Coronary artery disease requiring isolated CABG (n=1,673). Body mass index vs. Normal/overweight BMI was evaluated on Early mortality in the first 30 days after surgery (p=0.229). Body mass index was not significantly associated with 30-day mortality after coronary artery bypass grafting, but was an independent predictor of postoperative pulmonary complications (OR 1.6).
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