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June 2, 2016Journal of the American Heart AssociationOpen Access

Severe Obesity Is Associated With Increased Risk of Early Complications and Extended Length of Stay Following Coronary Artery Bypass Grafting Surgery

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Key result

Severe obesity (BMI ≥40.0) was associated with a higher risk of overall early complications (adjusted OR 1.56; 95% CI 1.21-2.01) and longer length of stay following coronary artery bypass grafting.

Why the study?

Does severe obesity increase the risk of early complications and extended length of stay in patients undergoing coronary artery bypass grafting surgery?

Population

7,560 patients who underwent coronary artery bypass grafting (CABG) surgery

Comparison

Higher body mass index categories vs Normal body mass index (BMI 18.5 to 24.9 kg/m²)

Design

Cohort

Follow-up

In-hospital

Authors

TTTasuku TeradaJJJeffrey JohnsonCNColleen M. Norris

Discussion

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Overview

May warrant enhanced perioperative monitoring in severe obesity; leaves open whether weight optimization reduces CABG complications.

Study Design

Type

Cohort (n=7,560)

Structured PICO

Does severe obesity increase the risk of early complications and extended length of stay in patients undergoing coronary artery bypass grafting surgery?

P
Population
7,560 patients who underwent coronary artery bypass grafting surgery, assessed for early adverse outcomes and in-hospital length of stay.
E
Exposure
Higher body mass index (BMI) categories (25.0-29.9, 30.0-34.9, 35.0-39.9, and ≥40.0 kg/m²)
C
Comparator
Normal body mass index (BMI 18.5 to 24.9 kg/m²)
O
Outcome
Incidence of early adverse outcomes (operative mortality, overall early complications, infection, renal and pulmonary complications) and in-hospital length of stayhard clinical

Main Result

Odds Ratio: 1.56 (95% CI 1.21–2.01)

Severe obesity (BMI ≥35.0) is an independent risk factor for early post-surgical complications, particularly infections, and extended length of stay following CABG.

Cite This Study

Terada et al. (2016) conducted a cohort in Coronary artery bypass grafting (n=7,560). Severe obesity (BMI ≥40.0 kg/m2) vs. Normal weight (BMI 18.5-24.9 kg/m2) was evaluated on Overall early complications (adjusted OR 1.56, 95% CI 1.21-2.01). Severe obesity (BMI ≥40.0) was associated with a higher risk of overall early complications (adjusted OR 1.56; 95% CI 1.21-2.01) and longer length of stay following coronary artery bypass grafting.

synapsesocial.com/papers/6a9ddaeefc007e1d4931d4aehttps://doi.org/10.1161/jaha.116.003282
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