What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Coronary artery disease or valvular heart disease requiring surgery (n=101). Intervention: Obesity (BMI ≥ 30 kg/m2) vs. Overweight (BMI 25-29.9 kg/m2). Primary outcome: Surgical reintervention due to sternal wound dehiscence (OR 13.6, 95% CI 1.1-162.9, p=0.046).

January 1, 2015Brazilian Journal of Cardiovascular SurgeryOpen Access

Impact of body mass index on the outcome in patients undergoing coronary artery bypass grafting and or valve replacement surgery

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Key result

Obesity was an independent predictor of increased risk of surgical reintervention due to sternal wound dehiscence (OR 13.6) and a reduced risk of bleeding (OR 0.05) compared to overweight patients.

Why the study?

Does obesity impact postoperative morbidities and mortality in patients undergoing CABG or valve replacement surgery?

Population

101 adult and elderly patients undergoing elective coronary artery bypass grafting, valve replacement, or…

Comparison

Obesity or Overweight vs Normal weight (BMI 18.5-24.9 kg/m2)

Design

Cross-sectional

Follow-up

From first day of admission until discharge or death

Authors

VCVinícius Eduardo Araújo Costa SFS Ferolla TRTâmara Oliveira dos Reis

Discussion

Member takes

Overview

May warrant heightened sternal surveillance in obese CABG/valve patients; hypothesis-generating for obesity's mixed effects and requires prospective validation.

Study Design

Type

Cross-Sectional (n=101)

Multicenter

Structured PICO

Does obesity impact postoperative morbidities and mortality in patients undergoing CABG or valve replacement surgery?

Population

101 adult and elderly patients undergoing elective coronary artery bypass grafting or valve replacement surgery at a single center in Brazil, followed until hospital discharge or death.

Exposure

Obesity (BMI ≥ 30 kg/m2) or Overweight (BMI 25-29.9 kg/m2)

Comparator

Normal weight (BMI 18.5-24.9 kg/m2)

Outcome

Association between BMI and postoperative morbidities and mortality (up to 30 days after surgery or hospital discharge)hard clinical

Main Result

Odds Ratio: 13.6 (95% CI 1.1–162.9)

Absolute Event Rate: 10% vs 0%

p-value: p=0.046

In patients undergoing CABG or valve replacement, obesity is associated with a higher risk of surgical reintervention for sternal wound dehiscence but a lower risk of postoperative bleeding.

Limitations

Small sample size
Not possible to evaluate the usefulness of BMI as a predictor of mortality in the multivariate analysis due to the low number of deaths
Unable to evaluate BMI as a predictor of mortality in multivariate analysis due to low number of deaths

Cite This Study

Costa et al. (2015) conducted a cross-sectional in Coronary artery disease or valvular heart disease requiring surgery (n=101). Obesity (BMI ≥ 30 kg/m2) vs. Overweight (BMI 25-29.9 kg/m2) was evaluated on Surgical reintervention due to sternal wound dehiscence (OR 13.6, 95% CI 1.1-162.9, p=0.046). Obesity was an independent predictor of increased risk of surgical reintervention due to sternal wound dehiscence (OR 13.6) and a reduced risk of bleeding (OR 0.05) compared to overweight patients.

synapsesocial.com/papers/6a9ddaeefc007e1d4931d4b0 https://doi.org/10.5935/1678-9741.20150027

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January 1, 2015Brazilian Journal of Cardiovascular SurgeryOpen Access

Impact of body mass index on the outcome in patients undergoing coronary artery bypass grafting and or valve replacement surgery

View Full Paper

Ask AI

Bookmark

Key result

Obesity was an independent predictor of increased risk of surgical reintervention due to sternal wound dehiscence (OR 13.6) and a reduced risk of bleeding (OR 0.05) compared to overweight patients.

Why the study?

Does obesity impact postoperative morbidities and mortality in patients undergoing CABG or valve replacement surgery?

Population

101 adult and elderly patients undergoing elective coronary artery bypass grafting, valve replacement, or…

Comparison

Obesity or Overweight vs Normal weight (BMI 18.5-24.9 kg/m2)

Design

Cross-sectional

Follow-up

From first day of admission until discharge or death

Authors

VCVinícius Eduardo Araújo Costa SFS Ferolla TRTâmara Oliveira dos Reis

Discussion

Member takes

Overview

May warrant heightened sternal surveillance in obese CABG/valve patients; hypothesis-generating for obesity's mixed effects and requires prospective validation.

Study Design

Type

Cross-Sectional (n=101)

Multicenter

Structured PICO

Does obesity impact postoperative morbidities and mortality in patients undergoing CABG or valve replacement surgery?

Population

101 adult and elderly patients undergoing elective coronary artery bypass grafting or valve replacement surgery at a single center in Brazil, followed until hospital discharge or death.

Exposure

Obesity (BMI ≥ 30 kg/m2) or Overweight (BMI 25-29.9 kg/m2)

Comparator

Normal weight (BMI 18.5-24.9 kg/m2)

Outcome

Association between BMI and postoperative morbidities and mortality (up to 30 days after surgery or hospital discharge)hard clinical

Main Result

Odds Ratio: 13.6 (95% CI 1.1–162.9)

Absolute Event Rate: 10% vs 0%

p-value: p=0.046

In patients undergoing CABG or valve replacement, obesity is associated with a higher risk of surgical reintervention for sternal wound dehiscence but a lower risk of postoperative bleeding.

Limitations

Small sample size
Not possible to evaluate the usefulness of BMI as a predictor of mortality in the multivariate analysis due to the low number of deaths
Unable to evaluate BMI as a predictor of mortality in multivariate analysis due to low number of deaths

Cite This Study

synapsesocial.com/papers/6a9ddaeefc007e1d4931d4b0 https://doi.org/10.5935/1678-9741.20150027

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

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