Key result
Among 22 peritoneal dialysis patients, paradoxical changes between blood pressure and fluid volume (n=10) were driven by significant decreases in total peripheral resistance.
Population
22 prevalent peritoneal dialysis patients exhibiting significant changes in blood pressure and extracellular…
Design
Cohort
Follow-up
2 months
Authors
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Hypothesis-generating for TPR as BP-volume mediator in PD; prospective trials needed before clinical adoption.
Cohort (n=22)
No
Total peripheral resistance is a key determinant of the blood pressure response to volume overload in peritoneal dialysis patients.
Tian et al. (2008) conducted a cohort in peritoneal dialysis (n=22). Paradoxical change between blood pressure and extracellular water vs. Parallel change between blood pressure and extracellular water was evaluated on Change in cardiac output and total peripheral resistance. Among 22 peritoneal dialysis patients, paradoxical changes between blood pressure and fluid volume (n=10) were driven by significant decreases in total peripheral resistance.
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