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July 1, 2002Peritoneal Dialysis International

Fluid status (ECV:BSA) was significantly higher in PD vs RTx patients (9.4 +/- 2.6 vs 8.6 +/- 1.2 L/m2, p < 0.05) and was significantly related to diastolic BP (r = 0.35-0.53, p < 0.05) and eccentric LVH (LVEDD, r = 0.41, p < 0.05).

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Why the study?

Does fluid status correlate with blood pressure and cardiovascular abnormalities in stable peritoneal dialysis patients compared to renal transplant patients?

Population

118 patients, comprising 41 stable peritoneal dialysis patients and 77 stable renal transplant patients.

Comparison

Assessment of fluid status, arterial… vs Stable renal transplant patients.

Design

Cross-sectional

Authors

CKConstantijn KoningsJKJeroen P. KoomanMSMarc Schonck

Discussion

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Overview

Fluid overload in PD was associated with diastolic BP and eccentric LVH; leaves open whether volume optimization improves CV outcomes versus RTx.

Structured PICO

Does fluid status correlate with blood pressure and cardiovascular abnormalities in stable peritoneal dialysis patients compared to renal transplant patients?

P
Population
118 patients, comprising 41 stable peritoneal dialysis (PD) patients (mean Kt/V urea 2.4 +/- 0.7) and 77 stable renal transplant (RTx) patients.
I
Intervention
Assessment of fluid status (via tracer dilution techniques), arterial distensibility (via carotid echography), cardiac structure (via echocardiography), and blood pressure (office and 24-hour ambulatory).
C
Comparator
Stable renal transplant (RTx) patients (used as a control population for fluid status comparison).
O
Outcome
Fluid status (extracellular volume corrected for body surface area) and its relationship with blood pressure and cardiac structure.surrogate

In peritoneal dialysis patients, overhydration is common and significantly correlates with diastolic blood pressure and eccentric left ventricular hypertrophy, highlighting the importance of fluid management.

Cite This Study

Konings et al. (2002) studied this question.

synapsesocial.com/papers/6a6fec0026a7f98052dc7b80https://doi.org/10.1177/089686080202200406
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Also Consider

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  1. 1Cardiac, Inflammatory and Metabolic Parameters: Hemodialysis versus Peritoneal Dialysis2014 · 27 citations
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  3. 3Hypertension and Left Ventricular Hypertrophy in Pediatric Peritoneal Dialysis Patients: Ambulatory Blood Pressure Monitoring and Echocardiographic Evaluation2006 · 20 citations
  4. 4Peripheral Resistance Modulates the Response to Volume Overload in Peritoneal Dialysis Patients2008 · 7 citations
  5. 5Cardiac geometry, function, and remodeling patterns in patients under maintenance hemodialysis and peritoneal dialysis treatment2021 · 14 citations