Key result
Conservative management with fluids and vasopressors for acute cardiac tamponade during electrophysiologic procedures resulted in 100% survival to hospital discharge, identical to invasive management.
Why the study?
Does conservative management with fluids and vasopressors result in similar clinical outcomes compared to invasive pericardiocentesis in patients with acute cardiac tamponade complicating EP procedures?
Observational (n=33)
No
Does conservative management with fluids and vasopressors result in similar clinical outcomes compared to invasive pericardiocentesis in patients with acute cardiac tamponade complicating EP procedures?
Absolute Event Rate: 100% vs 100%
Conservative management with fluids and vasopressors may be a safe and effective alternative to pericardiocentesis for a subset of patients with acute cardiac tamponade complicating EP procedures who lack a large effusion.
May support conservative management in select EP tamponade cases; leaves open need for prospective trials versus pericardiocentesis.
BACKGROUND: Cardiac perforation with tamponade is an infrequent occurrence during an electrophysiologic procedure. The customary approach to management includes volume resuscitation followed by pericardiocentesis. Such a procedure, however, is not without its own risk, especially when performed emergently. We hypothesized that some patients experiencing this type of complication can be managed successfully in a conservative fashion, without the need for an additional invasive procedure. METHODS: We retrospectively analyzed the clinical outcomes and echocardiographic features of 33 consecutive patients who experienced this complication during cardiac electrophysiology (EP) procedures performed at our institution from 1988 to 2007. Nineteen patients (58%) were managed conservatively with intravenous fluids and vasopressors (Group A). Fourteen patients (42%) were managed invasively with pericardiocentesis (Group B). RESULTS: The mean systolic blood pressure at diagnosis did not differ between the two groups (64 vs 71 mmHg, P = 0.134). The mean lengths of hospitalization (4.7 vs 4.9 days, P = 0.75) and survival to hospital discharge (100% in both groups) were also similar. A large pericardial effusion (>or=2 cm) was seen predominantly among Group B patients. There was a statistically significant temporal trend toward managing this type of complication invasively (P = 0.038). CONCLUSION: Among patients who experience cardiac perforation as an acute complication of EP procedure, there appears to be a role for conservative management in a subset of patients who do not have echocardiographic evidence of a large effusion and who respond well to initial stabilizing measures consisting of fluids and vasopressors.
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Kim et al. (2010) conducted an observational in Acute cardiac tamponade complicating electrophysiologic procedures (n=33). Conservative management (intravenous fluids and vasopressors) vs. Invasive management (pericardiocentesis) was evaluated on Survival to hospital discharge. Conservative management with fluids and vasopressors for acute cardiac tamponade during electrophysiologic procedures resulted in 100% survival to hospital discharge, identical to invasive management.
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