Key result
Activation of the sympathetic system by bilateral occlusion of carotid arteries decreased liver vascular volume by 40% in dogs without changing average blood flow or interstitial and cellular water spaces.
Authors
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Sympathetic modulation of hepatic capacitance warrants study in human shock or HF; leaves open translation from canine models to clinical volume management.
Cousineau et al. (1985) studied this question. Activation of the sympathetic system by bilateral occlusion of carotid arteries vs. Control conditions was evaluated on Liver vascular volume. Activation of the sympathetic system by bilateral occlusion of carotid arteries decreased liver vascular volume by 40% in dogs without changing average blood flow or interstitial and cellular water spaces.
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