What is the clinical evidence from this study?

Study design: Observational. Population: Dilated cardiomyopathy at sinus rhythm (n=45). Intervention: Dilated cardiomyopathy at sinus rhythm. Primary outcome: Prevalence of left ventricular (LV) and left atrial appendage (LAA) thrombus.

What question did this study set out to answer?

To evaluate the prevalence of left cardiac chamber thrombi and identify echocardiographic predictors of thrombus formation in dilated cardiomyopathy patients in sinus rhythm.

June 22, 2012Journal of Clinical Ultrasound

Prevalence of left chamber cardiac thrombi in patients with dilated left ventricle at sinus rhythm: The role of transesophageal echocardiography

View Full Paper

Ask AI

Bookmark

Key result

In patients with dilated cardiomyopathy at sinus rhythm without anticoagulation, left atrial appendage thrombus was present in 68.9% and left ventricular thrombus in 13.3%.

Population

45 patients with dilated cardiomyopathy of ischemic or idiopathic origin with mild to moderate systolic…

Design

Cross-sectional

Authors

ABAurora BakalliUniversity Clinical Center of Kosovo LGLjubica Georgievska‐IsmailSaints Cyril and Methodius University of Skopje DKDardan KoçinajUniversity Clinical Center of Kosovo

Discussion

Member takes

Implication

High thrombus prevalence in unanticoagulated sinus-rhythm dilated cardiomyopathy may indicate embolic risk; hypothesis-generating and requires prospective confirmation before practice change.

Key Points

To evaluate the prevalence of left cardiac chamber thrombi and identify echocardiographic predictors of thrombus formation in dilated cardiomyopathy patients in sinus rhythm.
Assessed 45 patients with ischemic or idiopathic dilated cardiomyopathy and mild-to-moderate systolic dysfunction in normal sinus rhythm without anticoagulation.
Conducted echocardiographic evaluations, including transesophageal echocardiography, to assess chamber dimensions and detect intracardiac thrombus formation.
Left ventricular thrombus was detected in 13.3% of patients, whereas left atrial appendage thrombus was present in 68.9%.
Left ventricular end-diastolic diameter correlated with left atrial volume (r = 0.59, p < 0.0001) and left ventricular thrombus (r = 0.38, p = 0.005).
Left atrial volume correlated with maximal left atrial appendage area (r = 0.34, p = 0.01), which was an independent predictor for left atrial appendage thrombus formation (p = 0.003).

Study Design

Type

Observational (n=45)

Structured PICO

Population

45 patients with dilated cardiomyopathy of ischemic or idiopathic origin with mild to moderate systolic dysfunction, at sinus rhythm and without anticoagulation therapy.

Exposure

Transesophageal echocardiography assessment

Outcome

Prevalence of intracardiac left chamber thrombus and/or spontaneous echo contrast, and clinical and echocardiographic predictors for LV, LA, and/or LAA thrombus formationsurrogate

Patients with dilated cardiomyopathy in sinus rhythm who are not on anticoagulation have a high prevalence of left atrial appendage thrombus (68.9%), suggesting a potential need to reconsider anticoagulation strategies in this population.

Cite This Study

Bakalli et al. (2012) conducted an observational in Dilated cardiomyopathy at sinus rhythm (n=45). Dilated cardiomyopathy at sinus rhythm was evaluated on Prevalence of left ventricular (LV) and left atrial appendage (LAA) thrombus. In patients with dilated cardiomyopathy at sinus rhythm without anticoagulation, left atrial appendage thrombus was present in 68.9% and left ventricular thrombus in 13.3%.

synapsesocial.com/papers/6a9de352e42e413fea367b7d https://doi.org/10.1002/jcu.21953

View Full Paper

Ask AI

Bookmark

Implication

High thrombus prevalence in unanticoagulated sinus-rhythm dilated cardiomyopathy may indicate embolic risk; hypothesis-generating and requires prospective confirmation before practice change.

Prevalence of left chamber cardiac thrombi in patients with dilated left ventricle at sinus rhythm: The role of transesophageal echocardiography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Prevalence of left chamber cardiac thrombi in patients with dilated left ventricle at sinus rhythm: The role of transesophageal echocardiography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider