Key result
The CARPREG score accurately predicted adverse maternal cardiac events, with observed complication rates of 5.8%, 23.5%, and 70.5% for scores of 0, 1, and ≥2, respectively.
Why the study?
Heart disease complicates 1-3% of pregnancies and is a major cause of maternal mortality and fetal complications, creating unique clinical challenges.
Does the CARPREG score predict maternal and fetal outcomes in pregnancies complicated by cardiac disease?
Observational (n=60)
No
Does the CARPREG score predict maternal and fetal outcomes in pregnancies complicated by cardiac disease?
The CARPREG score is a reliable clinical tool for predicting adverse maternal and fetal outcomes in pregnant women with cardiac disease, with observed complication rates closely matching predicted rates in a South Indian cohort.
Supports CARPREG for maternal risk stratification; extends validation to South Indian cohorts but leaves broader adoption open.
Background: Co-existing cardiac diseases in pregnancy poses unique challenges to anaesthesiologists and obstetricians. Heart diseases are estimated to complicate 1-3% of all pregnancies. It is a major contributing cause of maternal mortality and fetal complications.This study was designed to predict maternal and fetal outcomes in pregnancies complicated by cardiac diseases using Cardiac disease in Pregnancy (CARPREG) score. Aims and Objectives: 1.Predicting maternal mortality and adverse cardiac events during peripartum period using CARPREG score. 2.Evaluating neonatal outcomes in the pregnancies complicated by cardiac diseases. 3.To assess various cardiac conditions complicating pregnancies. Materials and Methods: A prospective observational study was designed to assess maternal and fetal outcomes using CARPREG score in 60 pregnancies complicated by cardiac diseases in the obstetric department of a tertiary care centre in South India between 2019-2021. CARPREG score includes New York Heart Association (NYHA) class, systolic ejection fraction, left ventricular obstruction and history of cardiac events assigning one point for each parameter; maximum being four. CARPREG score is validated for scores 0, 1 and 2 or more than 2 to be associated with cardiac event rates of 5%, 27% and 75% respectively.Results: Rheumatic heart disease (46.66%) followed by congenital heart diseases (31.66%) were the predominant cardiac diseases.
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Rashmi et al. (2022) conducted an observational in Pregnancies complicated by cardiac diseases (n=60). CARPREG score ≥1 vs. CARPREG score 0 was evaluated on Maternal cardiac complications. The CARPREG score accurately predicted adverse maternal cardiac events, with observed complication rates of 5.8%, 23.5%, and 70.5% for scores of 0, 1, and ≥2, respectively.
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