Key result
STA-MCA bypass surgery did not significantly affect resting cerebral blood flow but augmented collateral reserve in patients with severely impaired preoperative CO2 reactivity.
Why the study?
Does STA-MCA bypass surgery improve regional cerebral blood flow and CO2 reactivity in patients with neurologic disability?
Population
19 patients with neurologic disability undergoing STA-MCA bypass surgery
Comparison
STA-MCA bypass surgery vs Preoperative baseline
Design
Case_series
Follow-up
various times postoperatively
Authors
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May support bypass for reserve in impaired reactivity; hypothesis-generating and should not change practice without RCTs.
Observational (n=19)
Does STA-MCA bypass surgery improve regional cerebral blood flow and CO2 reactivity in patients with neurologic disability?
STA-MCA bypass surgery appears to augment collateral reserve in patients with severely impaired preoperative CO2 reactivity, rather than significantly affecting resting flow levels directly.
Halsey et al. (1982) conducted an observational in Neurologic disability with arterial lesion (n=19). STA-MCA bypass surgery vs. Preoperative baseline was evaluated on Regional cerebral blood flow (rCBF) at rest and CO2 reactivity. STA-MCA bypass surgery did not significantly affect resting cerebral blood flow but augmented collateral reserve in patients with severely impaired preoperative CO2 reactivity.
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