Key result
Continuous intravenous infusion of morphine resulted in patients spending 40.0% of the time below 94% oxygen saturation postoperatively, compared to 39.0% with intermittent intramuscular morphine.
Why the study?
Does continuous intravenous infusion of morphine compared to intermittent intramuscular morphine affect oxygen desaturation in patients following elective upper abdominal surgery?
Population
40 patients undergoing elective upper abdominal surgery
Comparison
Continuous intravenous infusion of morphine vs Intermittent intramuscular morphine
Design
Cohort
Follow-up
24 hours postoperatively
Authors
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Both regimens associated with comparable desaturation; leaves open optimal morphine route after abdominal surgery.
Cohort (n=40)
Does continuous intravenous infusion of morphine compared to intermittent intramuscular morphine affect oxygen desaturation in patients following elective upper abdominal surgery?
Absolute Event Rate: 40% vs 39%
Both continuous infusion and intermittent intramuscular morphine are associated with significant and comparable postoperative oxygen desaturation following elective upper abdominal surgery.
Kluger et al. (1992) conducted a cohort in Elective upper abdominal surgery (n=40). Continuous intravenous infusion of morphine vs. Intermittent intramuscular morphine was evaluated on Proportion of time with an oxygen saturation less than 94%. Continuous intravenous infusion of morphine resulted in patients spending 40.0% of the time below 94% oxygen saturation postoperatively, compared to 39.0% with intermittent intramuscular morphine.
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