Key result
A self-gated radial GA TPM sequence yielded highly similar velocities to conventional TPM (correlation 0.81-0.97) with superior black-blood contrast.
Why the study?
Does a self-gated radial GA TPM sequence improve image quality and velocity measurement compared to prospectively triggered radial TPM in healthy volunteers?
Does a self-gated radial GA TPM sequence improve image quality and velocity measurement compared to prospectively triggered radial TPM in healthy volunteers?
Effect estimate: correlation 0.81-0.97
The combination of Golden Angle Radial Sparse SENSE with image-based self-gating enables high-quality myocardial velocity measurements with superior black-blood contrast.
Self-gated radial GA TPM supports feasible velocity mapping with better contrast in volunteers; hypothesis-generating and leaves clinical translation open.
PURPOSE: To investigate the combination of Golden Angle Radial Sparse SENSE reconstruction with image-based self-gating (SG) for deriving high-quality TPM data from radial golden angle (GA) k-space data. METHODS: In 10 healthy volunteers, a self-gated radial GA TPM sequence (TPMSG ) was compared with a prospectively triggered radial TPM acquisition with conventional respiratory (RNAV) compensation (TPMref ). Image quality and velocities were compared for different regularization strengths λ in the CS reconstruction. RESULTS: Acquisitions and retrospective self-gating was successful in all cases. Contrast in TPMSG was superior to TPMref , because the blood saturation bands could be applied with full thickness without interference with the RNAV. Velocities from both acquisitions visually showed the same motion patterns and were quantitatively highly similar (correlation 0.81-0.97 and RMSE 0.08-0.21 cm/s). Strong temporal regularization ( λ∈0.3,0.4) led to reduced velocity peaks in TPMSG . For λ=0.2, image sharpness as well as velocity peaks of TPMSG were comparable to TPMRef . CONCLUSION: The combination of Golden Angle Radial Sparse SENSE with image-based self-gating allows measurement of velocities of the myocardium with superior black-blood contrast and full coverage of the cardiac cycle.
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Paul et al. (2015) studied Healthy (n=10). Self-gated radial GA TPM sequence (TPMSG) vs. Prospectively triggered radial TPM acquisition with conventional respiratory compensation (TPMref) was evaluated on Image quality and velocities (correlation 0.81-0.97). A self-gated radial GA TPM sequence yielded highly similar velocities to conventional TPM (correlation 0.81-0.97) with superior black-blood contrast.
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