Key result
Post-procedural cardiac troponin-I elevation following elective PCI did not significantly predict poor long-term outcomes, with major adverse cardiovascular events occurring in 33.3% vs 16.4%.
Why the study?
Does post-procedural cTn-I elevation predict major adverse cardiovascular events in patients undergoing elective PCI?
Cohort (n=100)
Does post-procedural cTn-I elevation predict major adverse cardiovascular events in patients undergoing elective PCI?
Post-procedural cTn-I elevation following elective PCI is frequent but does not significantly predict poor long-term clinical outcomes at 12 months.
Troponin elevation should not yet guide post-elective PCI surveillance or risk stratification; leaves open validation in larger prospective cohorts.
The objective of this study was to investigate the predictors and prognostic significance of post-procedural cardiac troponin (cTn)-I elevations in a consecutive series of patients who underwent elective percutaneous coronary intervention (PCI). cTn-I was measured in 100 patients immediately before and within 24 h after the elective PCI. Post-procedural cTn-I elevation was observed in 27 of the 100 patients. In multivariate analysis, basal haemoglobin values and the number of repeated balloon dilatations were found to be independent predictors of cTn-I elevation. During the follow-up period of 12 +/- 1.2 months, the cTn-I-positive group had more major adverse cardiovascular events than the cTn-I-negative group (33.3% versus 16.4%, respectively), but the difference was not significant. An increase in cTn-I levels following elective PCI procedures was frequent but did not predict a poor long-term outcome.
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İzgi et al. (2006) conducted a cohort in Elective percutaneous coronary intervention (PCI) (n=100). Post-procedural cardiac troponin (cTn)-I elevation vs. cTn-I-negative group was evaluated on Major adverse cardiovascular events (p=not significant). Post-procedural cardiac troponin-I elevation following elective PCI did not significantly predict poor long-term outcomes, with major adverse cardiovascular events occurring in 33.3% vs 16.4%.
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