Endothelial fenestrations and other vascular alterations in primary melanoma of the central nervous system

This is the authors' abstract. We don't add key points for this paper.

A primary malignant melanoma of the central nervous system is studied by light and electron microscopy. There were numerous endothelial fenestrae and basement membrane abnormalities in intrinsic tumor capillaries. It is felt that these vascular abnormalities may play a role in explaining why these tumors have an increased incidence of bleeding. No characteristic findings were encountered which would help distinguish this tumor from one of peripheral origin.