Key result
Outpatient use of tinzaparin during transition to warfarin for VTE was associated with a 0.7% rate of recurrent VTE and a 3.6% rate of major bleeding.
Why the study?
Is outpatient tinzaparin safe and effective during transition to warfarin in patients with acute venous thromboembolism?
Population
178 outpatients with acute venous thromboembolism treated within the University of California Davis…
Design
Cohort
Follow-up
4 to 12 weeks
Authors
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Supports outpatient tinzaparin bridging for VTE; hypothesis-generating and requires randomized confirmation before practice change.
Cohort (n=178)
No
Is outpatient tinzaparin safe and effective during transition to warfarin in patients with acute venous thromboembolism?
Outpatient use of tinzaparin during transition to warfarin appears feasible and safe for the treatment of venous thromboembolism, including pulmonary embolism.
Dager et al. (2005) conducted a cohort in Venous thromboembolism (DVT or PE) (n=178). Tinzaparin was evaluated on Incidence of recurrent thromboembolism. Outpatient use of tinzaparin during transition to warfarin for VTE was associated with a 0.7% rate of recurrent VTE and a 3.6% rate of major bleeding.
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