Key result
Higher total physical activity in breast cancer survivors was associated with higher SDNN (28.8 vs 20.0; P=0.008) and SD2 indices (38.7 vs 29.2; P=0.005) compared to inactive women.
Why the study?
Breast cancer survivors frequently present cardiac autonomic dysfunction, and the association between cardiac autonomic modulation and physical activity across different domains needed to be evaluated.
Does higher physical activity improve cardiac autonomic modulation in breast cancer survivors?
Cross-Sectional (n=99)
Does higher physical activity improve cardiac autonomic modulation in breast cancer survivors?
Absolute Event Rate: 28.8% vs 20%
p-value: p=0.008
Higher total physical activity is associated with better cardiac autonomic modulation in breast cancer survivors, highlighting the importance of physical activity for cardiovascular health in this population.
Higher total PA was associated with better CAM in breast cancer survivors; leaves open causality and domain-specific effects, warranting prospective trials.
BACKGROUND: Breast cancer survivors frequently present cardiac autonomic dysfunction. Physical activity (PA) has been associated with better cardiac autonomic modulation (CAM) in breast cancer survivors. OBJECTIVE: This study aimed to analyze the association between CAM and PA levels performed in different domains (work and occupation, sport and exercise, and leisure time and commuting) in breast cancer survivors. METHODS: This is a cross-sectional study with 99 breast cancer survivors (age, 55.3 ± 10.4 years). Cardiac autonomic modulation was assessed by heart rate variability, and PA levels at work and occupation, sport and exercise, and leisure time and commuting were assessed using the Baecke PA questionnaire. The sum of these 3 domains provided the total PA. The Mann-Whitney test was used to compare CAM between active and inactive women in different domains of PA. RESULTS: Cardiac autonomic modulation was similar between active and inactive women in the different domains ( P > .05). However, when considering the total PA, active breast cancer survivors presented higher SDNN (average standard deviation of all normal RR intervals) (20.0 ± 13.4 vs 28.8 ± 14.0; P = .008) and SD2 (standard deviation of the long-term intervals between consecutive heartbeats) indices (29.2 ± 17.3 vs 38.7 ± 19.9; P = .005) compared with their inactive counterparts. CONCLUSION: Breast cancer survivors with higher total PA presented better CAM compared with their less active peers. IMPLICATIONS FOR PRACTICE: The results of this study are promising and show the importance of increasing PA levels in different domains for the maintenance of cardiovascular health among breast cancer survivors.
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Palma et al. (2022) conducted a cross-sectional in Breast cancer (n=99). Total physical activity vs. Inactive women was evaluated on SDNN (average standard deviation of all normal RR intervals) (p=0.008). Higher total physical activity in breast cancer survivors was associated with higher SDNN (28.8 vs 20.0; P=0.008) and SD2 indices (38.7 vs 29.2; P=0.005) compared to inactive women.
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