Key result
Left ventricular hypertrophy by ECG in pregnancies with chronic hypertension was associated with higher rates of superimposed preeclampsia (68% vs 41%; OR 3.01; 95% CI 1.1-8.5; p=0.022).
Why the study?
Does left ventricular hypertrophy by ECG predict superimposed preeclampsia and adverse obstetrical outcomes in pregnancies with chronic hypertension?
Population
218 singleton pregnancies with chronic hypertension who carried the pregnancy beyond 20 weeks and planned to…
Comparison
Left ventricular hypertrophy (LVH) by ECG criteria vs Without left ventricular hypertrophy by ECG…
Design
Cohort
Follow-up
until delivery
Authors
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ECG LVH may flag higher SIP risk in CHTN; leaves open whether screening alters management.
Cohort (n=218)
No
Does left ventricular hypertrophy by ECG predict superimposed preeclampsia and adverse obstetrical outcomes in pregnancies with chronic hypertension?
Odds Ratio: 3.01 (95% CI 1.1–8.5)
Absolute Event Rate: 68% vs 41%
p-value: p=0.022
In pregnancies with chronic hypertension, the presence of left ventricular hypertrophy on ECG is associated with a 3-fold increased odds of superimposed preeclampsia and lower birthweight.
Duncan et al. (2018) conducted a cohort in Pregnancies with chronic hypertension (n=218). Left ventricular hypertrophy (LVH) by ECG criteria vs. Mothers without LVH was evaluated on Superimposed preeclampsia (SIP) (OR 3.01, 95% CI 1.1-8.5, p=0.022). Left ventricular hypertrophy by ECG in pregnancies with chronic hypertension was associated with higher rates of superimposed preeclampsia (68% vs 41%; OR 3.01; 95% CI 1.1-8.5; p=0.022).
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