Key result
Chronic hypertension during pregnancy was associated with higher rates of cesarean delivery (OR 2.7; 95% CI 2.4-3.0) and perinatal mortality, independent of superimposed preeclampsia.
Why the study?
Does chronic hypertension increase the risk of adverse pregnancy outcomes independent of superimposed preeclampsia in singleton term deliveries?
Population
113,156 singleton term (>36 weeks) deliveries occurring between 1988 and 1999
Comparison
Chronic hypertension during pregnancy vs Pregnancies without chronic hypertension
Design
Cohort
Follow-up
Perinatal period
Authors
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May support intensified antenatal surveillance in chronic hypertension; leaves open whether BP optimization reduces cesarean or mortality risks.
Cohort (n=113,156)
Does chronic hypertension increase the risk of adverse pregnancy outcomes independent of superimposed preeclampsia in singleton term deliveries?
Odds Ratio: 2.7 (95% CI 2.4–3)
Chronic hypertension during pregnancy is independently associated with adverse pregnancy outcomes, including perinatal mortality and intrauterine growth restriction, regardless of superimposed preeclampsia.
Vanek et al. (2004) conducted a cohort in Pregnancy (n=113,156). Chronic hypertension vs. No chronic hypertension was evaluated on Cesarean delivery (OR 2.7, 95% CI 2.4-3.0). Chronic hypertension during pregnancy was associated with higher rates of cesarean delivery (OR 2.7; 95% CI 2.4-3.0) and perinatal mortality, independent of superimposed preeclampsia.
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